代表性学术论文(*表示通讯联系人,#表示共同第一作者)

 

 2020

[47]  Feng Chen#, Jing Xue#, Jin Zhang, Min Bai, Xu Yu, Chunhai Fan and Yongxi Zhao*. Differentiated Visualization of Single-Cell 5-Hydroxymethylpyrimidines with Microfluidic Hydrogel Encoding. Journal of the American Chemical Society, 2020, 142, 6, 2889-2896 (IF 14.695)PDF

2019

[46]  Feng Chen#, Min Bai# Xiaowen Cao, Yue Zhao, Jing Xue, Yongxi Zhao*.  Click-encoded rolling FISH for visualizing single-cell RNA polyadenylation and structures. Nucleic Acids Research, 2019, 47(22): e145-e145  (IF 11.147)PDF

[45] Yue Zhao, Xiaoxing Fang, Feng Chen, Min Bai, Chunhai Fan, Yongxi Zhao*. Locus-patterned sequence oriented enrichment for multidimensional gene analysis. Chemical Science, 2019, 10, 8421-8427(IF 9.556)PDF 

[44] Yu XuNa Wu, Feng Chen, Jing Wei, Yongxi Zhao*. Engineering Microfluidic chip for Circulating Tumor Cells: From Enrichment, Release to Single Cell Analysis. Trends in Analytical Chemistry, 2019,117,27-38 (IF 8.428)  PDF 

[43] Jing Xue#, Feng Chen#Min Bai, Xiaowen Cao, Ping Huang, and Yongxi Zhao*. All-in-one Synchronized DNA Nanodevices Facilitating Multiplexed Cell Imaging. Analytical Chemistry, 2019, 91, 4696-4701 (IF 6.350)  PDF 

[42] Feng Chen#, Jing Xue#, Min Bai, Jing Qin, Yongxi Zhao*. Programming in situ accelerated DNA walkers in diffusion-limited microenvironments. Chemical Science, 2019, 10, 3103-3109 (IF 9.556) PDF 

 

2018

[41] Na Wu, Feng Chen, Yue Zhao, Yu Xu, Jing Wei and Yongxi Zhao*Functional and Biomimetic DNA Nanostructures on Lipid Membranes. Langmuir,  2018, 34(49), 14721-14730 (IF 3.683) PDF 

 

[40] Dongzhen Chen, Xiaodong Zhu, Jian Huang, Gen Wang, Yue Zhao, Feng Chen, Jing Wei, Zhongxiao Song, and Yongxi Zhao*. Polydopamine @ Gold Nanowaxberry Enabling Improved SERS Sensing of Pesticides, Pollutants and Explosives in Complex Samples. Analytical Chemistry, 2018, 90, 9048−9054(IF 6.350) PDF 

 

[39Jing Wei#, Gen Wang#, Feng Chen#, Min Bai, Yan Liang, Huanting Wang, Dongyuan ZhaoYongxi Zhao*. Sol-gel Synthesis of Metal-Phenolic Coordination Spheres and Their Derived Carbon Composites. Angewandte Chemie International Edition, 2018, 57, 9838 –9843 (IF 12.257) PDF 

 

[38Feng Chen#, Min Bai#Yue Zhao, Ke Cao, Xiaowen Cao, Yongxi Zhao*. MnO2 Nanosheet-Powered Janus Protection DNA Nanomachines Supporting Robust RNA Imagings. Analytical Chemistry, 2018, 90(3): 2271-2276(IF 6.350) PDF 

[37Yue Zhao, Feng Chen, Jing Qin, Jing Wei, Wenhua Wu and Yongxi Zhao*.Engineered Janus probes modulate nucleic acid amplification to expand the dynamic range for direct detection of viral genomes in one microliter crude serum samplesChemical Science,  20189:392-397 (IF 9.556)PDF  

 [36 Min Bai, Xiaowen Cao, Feng Chen, Yue Zhao, Yongxi Zhao*. A Förster Resonance Energy Transfer Ratiometric Probe Based on Quantum Dot-Cresyl Violet for Imaging Hydrogen Sulfide in Living Cells. Chinese Journal of Analytical Chemistry,  2018, 46(1):39-47 (IF 0.931)PDF 

 

2017

[35] Feng Chen#, Min Bai#, Ke Cao, Yue Zhao, Xiaowen Cao, Jing Wei, Na Wu, Jiang Li, Lihua Wang, Chunhai Fan, and Yongxi Zhao* .Programming Enzyme-Initiated Autonomous DNAzyme Nanodevices in Living Cells. ACS Nano. 2017, 11:11908-11914 (IF 13.903)PDF 

 

[34] Feng Chen, Min Bai, Ke Cao, Yue Zhao, Jing Wei, Yongxi Zhao*. Fabricating MnO2 Nanozymes as Intracellular Catalytic DNA Circuit Generators for Versatile Imaging of  Base-Excision Repair in Living Cell. Advanced Functional Materials. 2017, 27, 1702748 (IF 15.621) PDF  

[33]  Feng Chen#, Xuyao Wang#, Xiaowen Cao Yongxi Zhao*.  Accurate Electrochemistry Analysis of Circulation Methylated DNA from Clinical Plasma Based on Paired-End Tagging and Amplifications. Analytical Chemistry, 2017, 89: 10468-10473. (IF 6.350) PDF

[32]  Jing Xue, Feng Chen, Min Bai, Xu Yu, Jing Wei, Ping Huang, Yongxi Zhao*.  DNA-Mediated Assembly of Gold Nanoparticles and Its Applications in Bioanalysis. ChemNanoMat,  2017, 3: 725-735.(IF 3.379)  PDF

 

[31] Xuyao Wang#, Feng Chen#, Dexin Zhang, Yue Zhao, Jing Wei, Lihua Wang, Shiping Song, Chunhai Fan, Yongxi Zhao*. Single copy-sensitive electrochemical assay for circulating methylated DNA in clinical samples with ultrahigh specificity based on a sequential discrimination-amplification strategy. Chemical Science, 2017, 8: 4764-4770. (IF 9.556) PDFOutside Back Cover

 

[30] Jing Wei, Yaoxin Hu, Yan Liang, Biao Kong, Zhanfeng Zheng, Jin Zhang, San Ping Jiang, Yongxi Zhao*, Huanting Wang*. Graphene Oxide/Core-shell Structured Metal-Organic Frameworks Nano-sandwiches and Their Derived Cobalt/N-doped Carbon Nanosheets for Oxygen Reduction Reaction. Journal of Materials Chemistry A, 2017, 5: 10182-10189(IF 10.733) PDF  Back Cover

 

[29] Jian Huang#, Dayan Ma#, Feng Chen, Dongzhen Chen, Min Bai, Kewei Xu, Yongxi Zhao* Green in Situ Synthesis of Clean 3D Chestnut-Like Ag/WO3-x Nanostructures for Highly Efficient, Recyclable and Sensitive SERS Sensing. ACS Applied Materials & Interfaces, 2017, 9: 7436-7446. (IF 8.456)    PDF

  

2016 年

[28]Yue Zhao, Huaqing Liu, Feng Chen, Min Bai, Yongxi Zhao*. Fidelity quantification of mercury(II) ion via circumventing biothiols-induced sequestration in enzymatic amplification system. RSC Advances, 2016, 6: 80296-80301.  (IF 3.049)  PDF

 

[27]Yue Zhao, Huaqing Liu, Feng Chen, Min Bai, Junwu Zhao*,Yongxi Zhao*. Trifunctional Molecular Beacon-Mediated Quadratic Amplification for Highly Sensitive and Rapid Detection of Mercury(II) Ion with Tunable Dynamic Range. Biosensors and Bioelectronics, 2016, 86: 892-898. (IF 9.518)  PDF

[26]Dongzhen Chen, Zhongxiao Song, Feng Chen, Jian Huang, Jing Wei, Yongxi Zhao*. Simply Controllable Growth of Single Crystal Plasmonic Au-Ag Nano-spines with Anisotropic Multiple Site for Highly Sensitive and Uniform Surface-Enhanced Raman Scattering SensingRSC Advances, 2016, 6: 66056-66065 (IF 3.049)  PDF

     

[25]Feng Chen#, Manli Lin#, Yue Zhao, Yongxi Zhao*. Catalase-functionalized SiO2 nanoparticles mediate growth of gold nanoparticles for plasmonic biosensing of attomolar microRNA with the naked eye. RSC Advances, 2016, 6: 15709-15715. (IF 3.049) PDF 

                                                                                                                                                               

2015

  

[24]Feng Chen, Dexin Zhang, Qing Zhang, Xiaolei Zuo, Chunhai Fan, Yongxi Zhao*. Zero-background helicase-dependent amplification and its application to reliable assay of telomerase activity in cancer cell by eliminating primer-dimer artifacts. ChemBioChem, 2016, 17: 1171-1176. (IF 2.593) PDF

 

[23]Yongxi Zhao*, Feng Chen, Qian Li, Lihua Wang, Chunhai Fan*.Isothermal amplification of nucleic acids.Chemical Reviews, 2015 , 115: 12491-12545. (IF 54.301) PDF

 

[22]Jian Huang#, Dayan Ma#, Feng Chen, Min Bai, Kewei Xu,Yongxi Zhao*. Ag nanoparticles decorated cactus-like Ag dendrites/Si nanoneedles as highly efficient 3D SERS substrates toward sensitive sensing. Analytical Chemistry, 2015, 87: 10527-10534. (IF 6.350) PDF

[21]Feng Chen, Chunhai Fan,Yongxi Zhao*. Inhibitory impact of 3′-terminal 2′-O-methylated small silencing RNA on target-primed polymerization and unbiased amplified quantification of the RNA in arabidopsis thaliana. Analytical Chemistry, 2015, 87: 8758-8764.(IF 6.350) PDF

 

 

 

[20]Feng Chen,Yue Zhao,Chunhai Fan,Yongxi Zhao*. Mismatch extension of DNA polymerases and high-accuracy single nucleotide polymorphism diagnostics by gold nanoparticle-improved isothermal amplification. Analytical Chemistry, 2015, 87: 8718-8723.(IF 6.350)

PDF

 

[19]Haobin Chen, Kaiwen Chang, Xiaoju Men, Kai Sun, Xiaofeng Fang, Chi Ma, Yongxi Zhao, Shengyan Yin, Weiping Qin, Changfeng Wu*. Covalent patterning and rapid visualization of latent fingerprints with photo-cross-linkable semiconductor polymer dots. ACS Applied Materials & Interfaces, 2015,7: 14477-14484.(IF 8.456) PDF

[18]Jian Huang, Feng Chen, Qing Zhang, Yonghua Zhan, Dayan Ma*, Kewei Xu*, Yongxi Zhao*. 3D silver nanoparticles decorated zinc oxide/silicon heterostructured nanomace arrays as high-performance surface-enhanced raman scattering substrates. ACS Applied Materials & Interfaces, 2015,7: 5725-5735.(IF 8.456) PDF

 

2014

[17]Yongxi Zhao*, Feng Chen, Qing Zhang, Yue Zhao, Xiaolei Zuo, Chunhai Fan*. Polymerase/nicking enzyme synergetic isothermal quadratic DNA machine and its application for one-step amplified biosensing of lead (II) ions at femtomole level and DNA methyltransferase.NPG Asia Materials,2014,6:e131.(IF 8.052PDF

[16]Qing Zhang#, Feng Chen#, Feng Xu, Yongxi Zhao*, Chunhai Fan. Target-triggered three-way junction structure and polymerase/nicking enzyme synergetic isothermal quadratic DNA machine for highly specific, one-step, and rapid microRNA detection at attomolar level. Analytical Chemistry,2014, 86 (16):8098-8105.(IF 6.350) PDF

[15]Yongxi Zhao*, Feng Chen, Manli Lin, Chunhai Fan*. A methylation-blocked cascade amplification strategy for label-free colorimetric detection of DNA methyltransferase activity. Biosensors and Bioelectronics,2014,54:565-570.(IF 9.518) PDF

 

[14]Yongxi Zhao*, Feng Chen, Yayan Wu, Yanhua Dong, Chunhai Fan. Highly sensitive fluorescence assay of DNA methyltransferase activity via methylation-sensitive cleavage coupled with nicking enzyme-assisted signal amplification. Biosensors and Bioelectronics, 2013,42:56-61. (IF 9.518) PDF

 

 2013

[13]Yongxi Zhao*, Lin Qi, Feng Chen, Yue Zhao, Chunhai Fan. Highly sensitive detection of telomerase activity in tumor cells by cascade isothermal signal amplification based on three-way junction and base-stacking hybridization. Biosensors and Bioelectronics, 2013,41:764-770.(IF 8.173) PDF

[12]Feng Chen, Yongxi Zhao*, Lin Qi, Chunhai Fan. One-step highly sensitive florescence detection of T4 polynucleotide kinase activity and biological small molecules by ligation-nicking coupled reaction-mediated signal amplification. Biosensors and Bioelectronics, 2013,47:218-224. (IF 8.173) PDF

[11]Feng Chen, Yongxi Zhao*. Methylation-blocked enzymatic recycling amplification for highly sensitive fluorescence sensing of DNA methyltransferase activity. Analyst,2013,138:284-289.(IF 3.864) PDF

[10]Junyu Zhang, Qian Cao, Shaowu Li, Xiaoyun Lu, Yongxi Zhao, Jisong Guan, Jinchun Chen, Qiong Wu, Guoqiang Chen. 3-Hydroxybutyrate methyl ester as a potential drug against Alzheimer's disease via mitochondria protection mechanism. Biomaterials, 2013,30:7552-7562. (IF 8.806) PDF

2012

[9]Yongxi Zhao*, Lin Qi,Feng Chen,Yanhua Dong, Yu Kong,Yayan Wu, Chunhai Fan*. Ultrasensitive and selective detection of nicotinamide adenine dinucleotide by target-triggered ligation-rolling circle amplification. Chemical Communications,2012, 48:3354-3356. (IF 6.290) PDF

[8]Lin Qi, Yongxi Zhao*, Hui Yuan, Kai Bai,Yue Zhao, Feng Chen,Yanhua Dong,Yayan Wu. Amplified fluorescence detection of mercury(II) ions(Hg2+) using target-induced DNAzyme cascade with catalytic and molecular beacons. Analyst, 2012, 137:2799-2805. (IF 3.864) PDF

 

[7]Yongxi Zhao*, Lin Qi, Wejun Yang, Shuai Wei, Yaling Wang. Amplified fluorescence detection of Pb2+ using Pb2+-dependent DNAzyme combined with nicking enzyme-mediated enzymatic recycling amplification. Chinese Journal of Analytical Chemistry, 2012,40:1236-1240.(IF 0.824) PDF

2011年以前

[6]Graham Milne,Yongxi Zhao, Daniel T. Chiu*. High-precision measurement and analysis of colloidal monolayers.Analytical Chemistry, 2010, 82:3943-3949. (IF 6.350) PDF

[5]Jason S. Kuo,Yongxi Zhao, Perry G. Schiro, Laiying Ng, David S. W. Lim, J. Patrick Shelby, Daniel T. Chiu*. Deformability considerations in filtration of biological cells. Lab on a Chip, 2010, 10:837-842. (IF 5.995) PDF

[4]Jason S. Kuo,Yongxi Zhao, Laiying Ng, Gloria S. Yen, Robert M. Lorenz, David S. W. Lim, Daniel T. Chiu*. Microfabricating high-aspect-ration structures in polyurethanse-methacrylate(PUMA) disposable microfluidic devices. Lab on a Chip, 2009, 9:1951-1956. (IF 5.995) PDF

[3]Yongxi Zhao,Perry G. Schiro,Jason S. Kuo, Laiying Ng, Daniel T. Chiu*. Methold for the accurate preparation of cell-spiking standards. Analytical Chemistry, 2009, 81:1285-1290. (IF 6.350) PDF

[2]Jason S. Kuo, Laiying Ng, Gloria S. Yen, Robert M. Lorenz, Perry G. Schiro, J. Scott Edgar, Yongxi Zhao, David S. W. Lim, Peter B. Allen, Gavin D. M. Jeffries Daniel T. Chiu*. A new USP class VI-compliant substrate for manufacturing disposable microfluidic devices. Lab on a Chip,2009, 9:870-876. (IF 5.995,Cover Paper) PDF

 

[1]Yongxi Zhao, Yu Kong, Bo Wang*, Yayan Wu, Hong Wu. On-line concentration and determination of all-trans- and 13-cis- retinoic acids in rabbit serum by application of sweeping technique in micellar electrokinetic chromatography, Journal of Chromatography A, 2007, 1146:131-135. (IF: 3.716) PDF

 

专利

已授权专利:

1) 一种端粒酶活性检测试剂盒及其检测方法;赵永席,齐林,陈锋,赵越,张青;专利号:ZL 2012 10247413.0
2) 一种基于恒温级联核酸扩增的铅离子检测试剂盒及其检测方法;赵永席,张青,袁慧,王芳霞,董绘阳,白凯;专利号:ZL 2013 1 0218918.9
3) 一种基于级联恒温扩增的miRNA荧光检测试剂盒及方法;赵永席,陈锋,张青,田苗,赵越,林曼丽;专利号:ZL 2014 10043512.6
4) 一种基于纳米金颗粒的单核苷酸多态性检测方法;赵永席,陈锋;专利号:ZL 2015 10289305.3
5仙人掌结构的银枝晶/硅针尖纳米复合材料的制备方法;赵永席,马大衍,黄剑,徐可为,陈锋;专利号:ZL 2015 10508669.6
6) 消除引物二聚体的零背景解旋酶依赖体系及扩增方法和应用;赵永席,陈锋;专利号:ZL 2015 10579700.5
7) 一种基于无偏识别与恒温扩增的小RNA检测试剂盒及定量方法;赵永席,陈锋,赵越;专利号:ZL 2015 10164043.8
8) 刺状、花瓣状粗糙表面金银合金纳米材料的制备方法;赵永席,陈东圳,宋忠孝,黄剑,陈锋;专利号:ZL 2016 10438497.4
9) 基于恒温级联核酸扩增的汞离子检测试剂盒及其检测方法;赵永席,赵越,袁慧,刘华青,白凯,魏帅,杨卫军,王芳霞,王亚玲;专利号:ZL 2015 10696810.X
10) 一种基于双标记扩增的血浆循环甲基化DNA电化学检测方法及试剂盒;赵永席,陈锋曹晓文王旭耀;专利号:ZL 2017 10626465.1
11)一种杨梅状聚多巴胺核金壳的纳米复合材料及其制备方法;赵永席,陈东圳,宋忠孝;专利号:ZL 2018 100449095
12) 基于核酸恒温扩增技术检测汞离子的DNA结构探针;赵永席,赵越,刘华青,袁慧,董绘阳,白凯,王芳霞,杨卫军,魏帅;专利号:ZL 2016 10460403.3

已申请专利

1) 过氧化氢消除核酸恒温扩增检测汞离子时DTT干扰的方法;赵永席,赵越,王亚玲,袁慧,董绘阳,白凯,王芳霞,杨卫军,魏帅,刘华青;申请号:201610460402.9

2)  一种活细胞内原位加速的DNA马达及其制备方法和应用;赵永席,陈锋,薛静;申请号:201811345762.X

3)  一体化同步DNA纳米器件及其活细胞多靶标成像应用和成像方法;赵永席,薛静,陈锋,黄平;申请号:201910123442.8

4)  一种多靶标基因并行检测组合探针及其试剂盒的应用;赵永席,赵越,房晓星,陈锋;申请号:201910453561.X
 
5)  一种原位细胞RNA加尾与结构的成像方法;赵永席,陈锋,白敏,薛静;申请号:201910662069.3
 
6)  一种单细胞5-hmC的检测方法;赵永席,张进,薛静,陈锋;申请号:201911039085.3
 
7)  一种多重核酸指数扩增探针及其肿瘤多靶标检测应用;赵永席,赵越,付有兰;申请号:201911203844.5

 

 

 

 

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