Selected Publications

40. Zhiwei Cui, Dapeng Li, Shanshan Xu, Tianqi Xu, Shan Wu, Ayache Bouakaz, Mingxi Wan, Siyuan Zhang. Effect of scattered pressures from oscillating microbubbles on neuronal activity in mouse brain under transcranial focused ultrasound stimulation. Ultrasonics Sonochemistry. Ultrasonics Sonochemistry, 2020, 63:104935.

39. Siyuan Zhang, Shan Wu, Shaoqiang Shang, Xuewei Qin, Xin Jia, Dapeng Li, Zhiwei Cui, Tianqi Xu, Gang Niu, Ayache Bouakaz, and Mingxi Wan. Detection and Monitoring of Thermal Lesions Induced by Microwave Ablation Using Ultrasound Imaging and Convolutional Neural Networks. IEEE Journal of Biomedical and Health Informatics, 2019, online.

38. Zhiwei Cui, Dapeng Li, Yang Feng, Tianqi Xu, Shan Wu, Yibao Li, Ayache Bouakaz, Mingxi Wan, Siyuan Zhang. Enhanced neuronal activity in mouse motor cortex with microbubbles’ oscillations by transcranial focused ultrasound stimulation. Ultrasonics Sonochemistry, 2019, 59:104745.

37. Zhang SY, Xu TQ, Cui ZW, Shi W, Wu S, Zong YJ, Niu G, He XJ, and Wan MX. Time and frequency characteristics of cavitation activity enhanced by flowing phase-shift nanodroplets and lipid-shelled microbubbles during focused ultrasound exposures. Ultrasound in Medicine and Biology, 2019,45(8):2118-2132.

36. Shan Wu, Xuewei Wang, Shaoqiang Shang, Ranxiang Xu, Xuewei Qin, Lei Zhang, Junbo Duan, Supin Wang, Mingxi Wan, and Siyuan Zhang. Effect of logarithmic compression on ultrasonic Nakagami imaging for monitoring of microwave ablation. IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

35. Dapeng Li, Zhiwei Cui, Tianqi Xu, Shan Wu, Yabo Yang, Ayache Bouakaz, Mingxi Wan, and Siyuan Zhang. Focused ultrasound stimulation of the ventrolateral periaqueductal gray decreases blood pressure in spontaneously hypertensive rats.  IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

34. Zhiwei Cui, Dapeng Li, Tianqi Xu, Shan Wu, Ayache Bouakaz, Mingxi Wan, and Siyuan Zhang. Microbubble-enhanced ultrasonic neuromodulation of motor cortex of mouse. IEEE International Ultrasonics Symposium, Glasgow, Scotland, UK, October 6-9, 2019.

33. Wu S, Shang SQ, Wang XW, Wan MX and Zhang SY. An in vivo study of ultrasonic monitoring imaging of microwave ablation based on Nakagami statistic parameter. Journal of Biomedical Engineering,2019, 36(3):371-378.

32. Zhang SY, Shang SQ, Han YQ, Gu CM, Wu S, Liu SH, Niu G,  Ayache Bouakaz, and Wan MX. Ex vivo and in vivo monitoring and characterization of thermal lesions by high-intensity focused ultrasound and microwave ablation using ultrasonic Nakagami imaging. IEEE Transactions on Medical Imaging, 2018, 37(7):1701-1710.

31. Zhang SY, Xu RX, Shang SQ, Han YQ, Liu SH, Xu TQ, Gu CM, Zhu XG, Niu G, and Wan MX. In vivo monitoring of microwave ablation in a porcine model using ultrasonic differential attenuation coefficient intercept imaging. International Journal of Hyperthermia, 2018, 34(8):1157-1170.

30.Li DP, Zhang SY, Cui ZW, Yabo Yang, Ayache Bouakaz and Wan MX. Transcranial focused ultrasound stimulation decrease blood pressure in spontaneously hypertensive rats. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

29.Zhang SY, Shang SQ, Wu S, Zhang L, Wang SP and Wan MX. Ultrasound convolutional neural networks imaging for monitoring of microwave ablation. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

28.Xu TQ, Zhang SY, Cui ZW, Li DP, Mo F, Wu S and Wan MX. Effects of flowing lipid-shelled microbubbles and phase-shift nanodroplets on the characteristics of cavitation  during focused ultrasound exposure. IEEE International Ultrasonics Symposium, Kobe, Japan, October 22-25, 2018.

27. Zhang SY, Han YQ, Zhu XG, Shang SQ, Huang GJ, Zhang L, Niu G, Wang SP, and Wan MX. Feasibility of using ultrasonic Nakagami imaging for monitoring microwave-induced thermal lesion in ex vivo porcine liver. Ultrasound in Medicine and Biology, 2017,43(2):482-493.

26. Zhang SY, Cui ZW, Xu TQ, Liu P, Li DP, Shang SQ, Xu RX, Zong YJ, Niu G, Wang SP, He XJ, and Wan MX. Inverse effects of flowing phase-shift nanodroplets and lipid-shelled microbubbles on subsequent cavitation during focused ultrasound exposures. Ultrasonics Sonochemistry, 2017, 34(1):400-409.

25. Zhang SY, Li C, Zhou FY, Wang SP, and Wan MX. Evaluate thermal lesion using Nakagami imaging for monitoring of high-intensity focused ultrasound. AIP Conference Proceedings, 2017, 1816: 050002,1-5.

24. Zhang SY, Cui ZW, Li C, Zhou FY, Zong YJ, Wang SP, and Wan MX. Enhanced cavitation and heating of flowing polymer- and lipid-shelled microbubbles and phase-shift nanodroplets during focused ultrasound exposures. AIP Conference Proceedings, 2017, 1816: 070001,1-5.

 23. Zhang SY, Shang SQ, Han YQ, Xu RX, Liu SH, Zhang L, Wu S, Niu G, Wang SH, and Wan MX. Monitoring of microwave ablation in porcine liver using ultrasonic Nakagami imaging. IEEE International Ultrasonics Symposium,1-4, Washington, D.C., USA, September 6-9, 2017.

 22. Ding T, Zhi GG, Zhang SY, Lu YM, and Wan MX. Ultrasound imaging with enhanced lesion-to-bubble ratio based on wavelet transform for monitoring of high-intensity focused ultrasound. IEEE International Ultrasonics Symposium, Washington, D.C., USA, September 6-9, 2017.

21. Zhang SY, Xu TQ, Cui ZW, Liu SH, Li DP, Guo R, Wang JJ, Zong YJ, Niu G, and Wan MX. Compare ultrasound-mediated cavitation between flowing phase-shift nanodroplets and lipid-shelled microbubbles during focused ultrasound exposures.The 17th International Symposium on Therapeutic Ultrasound, China, Nanjing, May 31-june 2,2017. 

20. Zhang SY, Shang SQ, Han YQ, Xu RX, Gu CM,  Zhang L, Wu S, Niu G, and Wan MX. In vivo and ex vivo monitoring of thermal ablation in a porcine model using ultrasonic nakagami imaging.The 17th International Symposium on Therapeutic Ultrasound, China, Nanjing, May 31-june 2,2017. 

19. Wan MX, Zhang SY, Lu MZ, Hu H, Jing BW, Liu RN, and Zhong H. Strategy of High Efficiency and Refined High-intensity Focused Ultrasound and Ultrasound Monitoring Imaging of Thermal Lesion and Cavitation.  AIP Conference Proceedings, 2017, 1821: 060002.

18. Hu H,  Xu SS, Wang DY, Liu R, Yuan Y, Zhang SY, Wang SP, Wan MX. Ultrasonic concentration imaging of cavitation bubbles using Nakagami statistical model. IEEE International Ultrasonics Symposium,1-4, Tours, France, September 18-21, 2016.

17. Duan JB, Zhong H, Jing BW, Zhang SY, and Wan MX. Increasing axial resolution of ultrasonic imaging with a joint sparse representation model. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2016, 63(12):2045-2056.

16. Zhang SY, Cui ZW, Zhang L, Zhu XG, Xu TQ, Wang SP, He XJ, and Wan MX. Feasibility of acoustic evaluation of thermal lesions at bone-soft tissue interface of an ex vivo bovine bone exposed to high-intensity focused ultrasound. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

15. Song WD, Zhang SY, Wan JJ, and Wan MX. Monitoring imaging of lesions induced by high intensity focused ultrasound based on a matching pursuit method. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

14. Duan JB, Zhong H, Jing BW, Zhang SY, and Wan MX. Discover layered structure in ultrasound images with a joint sparse representation model. IEEE International Ultrasonics Symposium, 1-4, Taipei, China, October 21-24, 2015.

13. Zhang SY, Cui ZW, Wang SP, and Wan MX. Nearby thermal ablation and acoustic evaluation of surface thermal injury of an ex vivo bovine bone exposed to high-intensity focused ultrasound. The 15th International Symposium on Therapeutic Ultrasound, Utrecht, Netherlands, April 15-18, 2015.

12. Zhang SY, Li C, Zhou FY, Wan MX, and Wang SP. Enhanced lesion-to-bubble ratio on ultrasonic Nakagami imaging for monitoring of high-intensity focused ultrasound. Journal of Ultrasound in Medicine, 2014, 33(6):959-970.

11. Ding T, Zhang SY (Co-first author), Fu QY, Xu ZA, and Wan MX. Ultrasound line-by-line scanning method of spatial-temporal active cavitation mapping for high-intensity focused ultrasound. Ultrasonics, 2014, 54(1):147-155.

10. Xu SS, Zong YJ, Li WS, Zhang SY and Wan MX. Bubble size distribution in acoustic droplet vaporization via dissolution using an ultrasound wide-beam method. Ultrasonics Sonochemistry, 2014, 21(3):975-983. 

9. Zhang SY, Li C, Yin H, Wang SP, and Wan MX. Surface vibration and nearby cavitation of an ex vivo bovine femur exposed to high intensity focused ultrasound. Journal of the Acoustical Society of America, 2013, 134(2): 1656-1662.

8. Zhang SY, Zong YJ, Wan MX, Yu XJ, Fu QY, Ding T, Zhou FY, and Wang SP. Compare ultrasound-mediated heating and cavitation between flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures. Journal of the Acoustical Society of America, 2012, 131 (6): 4845-4855.

7. Zhang SY, Zhou FY, Wan MX, Wei M, Fu QY, Wang X, and Wang SP. Feasibility of using Nakagami distribution in evaluating the formation of ultrasound-induced thermal lesions. Journal of the Acoustical Society of America, 2012, 131 (6): 4836-4844.

6. Zhang SY, Qiao YZ, and Wan MX. Acoustic, thermal and sonoluminescence investigation of enhanced cavitation of flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures. Journal of the Acoustical Society of America, 2012, 131(4): 3228-3228.

5. Wan YY, Zhang SY, Zong YJ, and Wan MX. Formation of two-way Lamb waves and force potential wells using single conventional ultrasonic transducer and sheep horn shaped metal piece. Journal of the Acoustical Society of America, 2012, 131(4): 3339-3339.

4. Zhang SY, Ding T, Wan MX, Jiang HJ, Yang X, Zhong H, and Wang SP. Minimizing the thermal losses from perfusion during focused ultrasound exposures with flowing microbubbles. Journal of the Acoustical Society of America, 2011, 129(4): 2336-2344.

3. Zhang DC, Zhang SY, Wan MX, and Wang SP. A fast tissue stiffness-dependent elastography for HIFU-induced lesions inspection. Ultrasonics, 2011, 51(8):857-869.

2. Zhong H, Wan MX, and Zhang SY. Monitoring dynamic characteristics of treated region during high intensity focused ultrasound (HIFU) treatment. 2011 Proceedings of International Symposium on Bioelectronics and Bioinformatics, 2011, 88-91.

1. Zhang SY, Wan MX, Zhong H, Xu C, Liao ZZ, Liu HQ and Wang SP. Dynamic changes of integrated backscatter, attenuation coefficient and bubble activities during high-intensity focused ultrasound (HIFU) treatment. Ultrasound in Medicine and Biology, 2009, 35(11): 1828-1844.

 

 

 

 

 

 

 

Monographs

1.  Zhang SY, Wan MX, and ter Haar G,“Chapter 4 Cavitation enhanced thermal effects and their applications,” in Book: Cavitation in biomedicine: principles and techniques, Editor: Wan MX, Feng Y, and ter Haar G, Springer, 2015. ISBN: 978-94-017-7254-9.

2.  张思远,徐田奇万明习等2 治疗超声中生物组织温度场。万明习,冯怡,路舒宽,计算生物医学超声学,北京:科学出版社,2019 (ISBN: 978-7-03-059103-6, 获国家科学技术学术著作出版基金资助)。

Patents

 

12. Siyuan Zhang, Zhiwei Cui, Dapeng Li, Tianqi Xu, Shan Wu, Mingxi Wan.High-spatial-resolution ultrasonic neuromodulation method and system, USA, Application Number: 16/275,527. 

11. Siyuan Zhang, Shan Wu, Shaoqiang Shang, Zhiwei Cui, Tianqi Xu, Mingxi Wan. Recognition, monitoring, and imaging method and system for thermal ablation region based on ultrasonic deep learning, USA, Application Number: 16/278,371.

10.张思远,徐冉翔,崔智炜,李大鹏,徐田奇,尚少强,万明习。一种无线控制的可穿戴式超声神经刺激装置,中国,授权专利号:ZL201610327257.7 

9.张思远,崔智炜,徐冉翔,尚少强,李大鹏,徐田奇,李延海,万明习。可穿戴经颅超声神经刺激与电生理记录联合系统与方法,中国,授权专利号:ZL201610326489.0

8.张思远,王华,崔智炜,李大鹏,徐田奇,吴珊,万明习。一种高空间分辨率超声神经调控方法及系统,中国,授权专利号ZL201811036875.1 

7.张思远,吴珊,尚少强,崔智炜,徐田奇,万明习。基于超声深度学习的热消融区域识别监测成像方法与系统,中国,专利申请号:201811226651.7 

6.张思远,李大鹏,崔智炜,徐田奇,吴珊,杨雅博,万明习。一种基于超声神经刺激的无创血压调控系统,中国,专利申请号:201811081537.X

5.张思远,崔智炜,徐冉翔,李大鹏,尚少强,徐田奇,李延海,郑良,万明习。用于经颅超声神经刺激的脑部电生理信号记录装置及方法,中国,专利申请号:201610326628.X

4.张思远,朱兴广,韩玉强, 黄国静,尚少强, 徐田奇,万明习,段君博,钟徽。一种用于热凝固监测的超声回波统计参量成像系统与方法,中国,专利申请号:201610326626.0

3.张思远,尚少强,徐冉祥,吴珊,崔智炜,徐田奇,李大鹏,万明习。基于深度学习的生物组织热消融超声监控成像软件V1.0。中国,软件著作权,2018SR243321

2.万明习张思远,蒋胡杰,钟徽,丁婷,廖振中,王素品。一种瞬态物理过程中多模式和多参量同步检测成像监控系统及监控方法中国授权专利号: ZL200910023529.4

1.万明习,丁婷,柳杨张思远。聚焦超声空化及其微汽泡实时提取装置与检测方法中国授权专利号:ZL200910021773.7

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